Uranium in Satisfactory is among the most dangerous but essential materials for end-game power production and research. Uranium opens the door to advanced nuclear energy, but harvesting and processing it requires planning, protective gear, and environmental awareness. This comprehensive Satisfactory Uranium Guide will walk you through where to get Uranium, how to handle it safely, what recipes it's used in, and how to maximize its potential in your factory.

Uranium is a radioactive ore that you see after progressing to the M.A.M. (Molecular Analysis Machine) and opening Tiers 7 and 8. You're not going to use it early on in the game, but it's absolutely necessary when you're expanding your power grid and getting your energy output to the maximum with Nuclear Power Plants.
When mined or handled improperly, Uranium emits toxic radiation that can poison or kill your character. To avoid contamination, you must make Hazmat Suits, filters, and build your infrastructure with the utmost care.
Uranium is very rare and located in the hostile, late-game areas of the map. The three main Uranium node locations are as follows:
Tip: Scanning for Uranium using the Resource Scanner (press "V" and select Uranium) is a good idea. Don't forget to pack a Hazmat Suit and filters when you travel. The radiation already starts increasing well before you arrive at the node.
When you reach a Uranium node, putting in an extractor is only the beginning. You need to:
To avoid exposure to radiation, use hazmat suits and gas Filters and locate your extraction point away from your primary factory.
In order to use Uranium as fuel, you should refine raw Uranium into Uranium Fuel Rods. That involves:
These rods are then fed into Nuclear Power Plants to produce massive amounts of power.

Nuclear Power Plants are unlocked in Tier 8 and require advanced planning. You’ll need:
Once built, a single Nuclear Power Plant can generate as much as 2500 MW, enough to power giant factories with ease.
Uranium Fuel Rods power Nuclear Power Plants, producing large amounts of energy for late-game factory automation.
Radioactive waste is a heavy load in Satisfactory. During the combustion of Uranium Fuel Rods, the Nuclear Power Plant produces Nuclear Waste that can't be destroyed. There are two primary methods:
Important: Plutonium Waste is much more radioactive than Uranium Waste. Plan for much safer storage.
In order to avoid accidents, death, or contamination of your base, do the following:
Isolate Uranium processes, wear protective equipment, and avoid storing or processing Uranium near your main base.

Here are some of the most popular recipes which utilize Uranium:
These recipes typically happen in Blenders and Manufacturers, so make sure your power grid is prepared to deal with their use.
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You're likely exposed to radiation. Craft and wear a Hazmat Suit with fresh Gas Filters.
Check your supply lines for Sulfuric Acid or missing Aluminum Casings. Check for radiation damage to belts and storage as well.
No, Nuclear Waste cannot be disposed of. It must be stored or reprocessed.
Store it in a safe, isolated location or reprocess it later into Plutonium for future fuel purposes.
Mastery of Uranium in Satisfactory is a hallmark achievement for long-time players. From locating deadly deposits to building advanced Nuclear Plants and handling waste, every action requires planning, machinery, and precision. Refer to this guide as your guidebook to mastery of the radiation frontier—and don't forget that with great power comes radioactive responsibility.
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